Indications: non-depolarising muscle relaxant of intermediate duration; adjunct in anesthesia to facilitate endotracheal intubation.

Cautions: ventilatory support is mandatory for patients until adequate sponatenous respiration is restored.

Clinicians should be familiar with early signs of malignant hyperthemia before the start of any anesthesia.

Side Effects: anaphylactic reactions; itching and erythematous reactions at the site of injection; bronchospam and cardiovascular changes.

Dose: endotracheal intubation, 0.6 mg/kg body weight. Maintenance, 0.15 mg/kg body weight.

This should be reduced in long-term inhalational anesthesia to 0.075 - 0.1 mg/kg body weight.

Continuous infusion, a loading dose of 0.6 mg/kg body weight and when the block starts to recover, IV infusion should start. Child, same sensitivity as adults.

Neonates, not recommended