Indications: dermatophyte fungal infections of the skin; ringworm infections where oral therapy is considered appropriate renal and hepatic impairment; oral treatment should be used only when topical treatment is not practicable.

Side Effects abdominal discomfort, anorexia, nausea, diarrhoea; headache; rash and urticaria occasionally with arthralgia or myalgia; less commonly taste disturbance; rarely liver toxicity (including jaundice, cholestasis and hepatitis)—discontinue treatment; angioedema, dizziness, malaise, paraesthesia, hypoaesthesia, photosensitivity, serious skin reactions (including Stevens-Johnson syndrome and toxic epidermal necrolysis) —discontinue treatment if progressive skin rash; very rarely psychiatric disturbances, blood disorders (including leucopenia and thrombocytopenia), lupus erythematosus-like effect, and exacerbation of psoriasis.

Dose: adults, 250 mg once daily for 2-6 weeks in tinea pedis, 2-4weeks in tinea corporis, tinea criris and cutaneous candidiasis.

Nail infections, 250 mg once daily for 6 weeks - 3 months.

Toenail infections- longer treatment is required. child: usually for 2 weeks, tinea capitis, over 1 year, body-weight 10–20 kg, 62.5 mg once daily; body-weight 20–40 kg, 125 mg once daily; body-weight over 40 kg, 250 mg once daily.