This is a vitamin D analogue that affects cell division and differentiation.

Indications: plaque psoriosis

Cautions: pregnancy; not to be used on the face; careful hand washing after use is recommended; children; risk of hypercalcaemia if max. recommended weekly dose exceeded.

Contra-indications: hypersensitivity to the drug constituents; disorders of calcium metabolism.

Side Effects: transient local irritataion; facial dermatitis may occur. photosensitivity; skin atrophy.

Dose Cream or ointment apply once or twice daily; max. 100g weekly (less with scalp solution); child over 6 years, apply twice daily; 6–12 years max. 50g weekly; over 12 years max. 75g weekly.