(Tetracosactide) This is an analogue of corticotrophin (ACTH)

Indications: diagnosis of adrenocortical function.

Cautions: hypersensitivity to tetracosactrin or corticotrophin preparation, asthma or atopy.

Contra-indications: Same as for dexamethasone; the depot preparation is not suitable for use in neonates due to presence of benzyl alcohol as additive.

Side Effects: Same as for dexamethasone; hypersensitivity reactions including marked redness and pain at injection sit flushing, severe malaise, urticaria, pruritus, dyspnea, edema, anaphylaxis.

Dose: for the depot preparation, diagnostic (5-hour test), by IM injection, 1 mg as a single dose.

For the aqueous preparation, diagnostic (30-minute test), by IM or IV injection, 250 mcg as a single dose.