Indications: post-operative analgesia, therapeutic pain block, Obstetric anesthesia.

Cautions: epilepsy, hepatic impairment, impaired cardiac conduction, bradycardia.

Dose: Shall be adjusted according to the site of operation and response of patient.

Local infiltration block, up to max. which is 225 mg with epinephrine and 175 mg (or 150 mg in the British System) without epinephrine.

For epidural and caudal block, 25-150 mg, Peripheral nerve block, 12.5 mg max.

Retro bulbar block, 15-30 mg. Sympathetic block, 50-125 mg.

Spinal anesthesia, heavy preparation 5 mg/ml is used, 2- 4ml.

The 0.75% strength is contra-indicated for epidural anesthesia in obstetrics. It is recommended to give a test dose of 10-15 mg before epidural useNo more than 400 mg should be given daily.