Indications: drying secretions; reversal of excessive bradycardia; with neostigmine for reversal of non- depolarising neuromuscular block; antidote to organophosphorous poisoning, antispasmodic; bradycardia; cardiopulmonary resuscitation; eye.

Cautions: cardiovascular disease

Dose: Pre-medication, by IV injection, 300-600 mcg immediately before induction of anesthesia and in incremental doses of 100 mcg for the treatment of bradycardia.

By IM injection, 300 - 600 mcg 30 to 60 minutes before induction.

Child, 20 mcg/kg.

For control of muscarinic side effects of neostigmine in reversal of Competitive neuromuscular block, by IV injection 0.6-1.2 mg.