Indications: prophylaxis of clinical manifestations of cytomegalovirus infection in patients subjected to immunosuppressive therapy particularly in transplant recipients.

Cautions: pregnancy and breast-feeding; severe adverse reactions may be related to the rate of infusion. Patients should be observed for at least 20 minutes after administration. Special caution in patient with an amnestic known history of migraine.

Contra-indications: patients intolerant to homologous immunoglobulins.

Side Effects: chills, headache, fever, vomiting, allergic reactions, mild back pain.

Dose: administration should be initiated on the day of transplantation or the day prior to it in case of BMT.

A total of at least 6 doses at 2-3 weeks intervals should be given.