Indications: for use in corticosteroid responsive severe inflammatory skin disorders such as Atopic dermatitis, Seborrhoeic dermatitis, Lichen simplex chronicus, Psoriasis (particularly of the face and body folds) and Allergic contact dermatitis.Cream permits use in moist intertrigenous areas.

Caution Prolonged use may result in overgrowth if non- susceptible organisms, including fungi other than candida; Use with particular caution in facial dermatoses, and only for short periods. A rosacea-like faces may be produced. Use with caution near the eyes.

Contra-indications: patients with tuberculous lesions, topical or systemic viral infections. ophthalmic use, nor should it be applied in the external auditory canal of patients with perforated eardrums. pregnancy.

Side Effects Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acne form eruptions, hypo pigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria due to corticosteroid. Nystatin is well tolerated even with prolonged therapy. Irritation and cases of contact dermatitis have been reported. Delayed type hypersensitivity reactions have been reported during use of neomycin; sensitization has been reported following prolonged use. Ototoxicity and nephrotoxicity have been reported when applied to large surfaces or damaged skin. Sensitivity reactions to gramicidin have been reported.

Dose: Apply a thin film of ointment or rub the cream to the affected areas 2 or 3 times daily.

Pregnancy: Teratogenic