This is an angiotensin-converting enzyme inhibitor. Indications: all grades of essential hypertension and renovascular hypertension where standard therapy ineffective or inappropriate; congestive heart failure (adjunct). Cautions: (See ACE-inhibitors); severe hepatic impairment.

Contra-indications: (See ACE-inhibitors)

Side Effects: (See ACE-inhibitors); dyspnea, asthenia, blurred vision,. Less commonly dry mouth, peptic ulcer, anorexia, ileus, arrhythmias, palpitation, flushing, confusion nervousness, drowsiness, insomnia, vertigo etc..

Dose: hypertension, used alone initially 5 mg daily; used in addition to a diuretic, in elderly patients, or in renal impairment, initially 2.5 mg daily; usual maintenance dose 10-20 mg daily; max. 40 mg daily. Heart failure, with a diuretic, dose initially, 2.5 mg daily under close hospital supervision. Usual maintenance dose, 10-20 mg daily in 1-2 divided doses.