Drug Information
Drug Generic Name | CARGLUMIC ACID |
Drug Class | DRUGS USED IN METABOLIC DISORDERS |
Chapter | Nutrition And Blood |
Indications: hyperammonaemia due to N- acetylglutamate synthase deficiency and organic acidaemia under specialist supervision Side Effects: sweating; less commonly diarrhoea, vomiting, bradycardia, pyrexia Dose: Hyperammonaemia due to N-acetylglutamate synthase deficiency, ADULT and CHILD initially 100–250 mg/kg daily in 2–4 divided doses immediately before food, adjusted according to plasma–ammonia concentration; maintenance 10–100 mg/kg daily in 2–4 divided doses. Hyperammonaemia due to organic acidaemia, ADULT and CHILD initially 100–250 mg/kg daily in 2–4 divided doses immediately before food, adjusted according to plasma- ammonia concentration. |
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