Indications: hyperphosphataemia in patients on haemodialysis or peritoneal dialysis.

Cautions: gastro-intestinal disorders

Contra-indications: bowel obstruction

Side Effects: nausea, vomiting, abdominal pain, constipation, diarrhoea, dyspepsia, flatulence; very rarely intestinal obstruction; also reported intestinal perforation, ileus, diverticulitis, pruritus, rash.

Dose: ADULT over 18 years, initially 2.4–4.8 g daily in 3 divided doses with meals, adjusted according to serum- phosphate concentration (usual dose range 2.4–12 g daily in 3 divided doses)