Indications: Vitamin-K deficiency in neonates; haemorrhage associated with over-dosage of anti- coagulants; hypoprothrombinemia due to anti-coagulants without haemorrhage.

Cautions: IV injection should be given very slowly.

Dose: neonate, by IM injection, 1mg.

Alternatively, by mouth, 2 doses of the colloidal (mixed micelle MM) preparation 2mg should be given in the first week. For breast-fed babies a third dose of 2mg is given at 1 month of age. The third dose is omitted in formula- fed babies because formula feeds contain vitamin K. Haemorrhage due to anti-coagulant overdosage, 2.5mg to 20mg by slow IV injection.