Drug Information
Drug Generic Name | CALCIUM FOLINATE (CALCIUM LEUCOVORIN) |
Drug Class | ANTIMETABOLITES AND RELATED THERAPY |
Chapter | Malignant Disease & Immunosuppression |
Indications: High dose methotrexate therapy (folate rescue); inadvertent overdose of methotrexate; with fluorouracil in the palliative treatment of advanced colorectal cancer. Cautions: not indicated for pernicious anaemia or other megaloblastic anaemias due to vitamin B12 deficiency; pregnancy; breastfeeding. Contra-indications: intrathecal injection is contraindicated. Side effect: allergic reactions; pyrexia after parenteral administration |
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