Drug Information
| Drug Generic Name | CISPLATIN |
| Drug Class | PLATINUM COMPOUNDS |
| Chapter | Malignant Disease & Immunosuppression |
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This is a platinum-containing complex with action similar to alkylating agents. Indications: metastatic testicular or ovarian tumours; advanced bladder cancer. Cautions: reduce dose in renal impairment. Contra-indications: pregnancy & breast feeding. Side Effects: severe nausea, vomiting, nephrotoxicity (pretreatment hydration recommended and the creatinine clearance should be closely monitored), myelo-toxicity, ototoxicity (high tone hearing loss and tinnitus), peripheral neuropathy, and hypomagnesaemia. |
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