Indications: BROAD SPECTRUM antibacterial indicated for the treatment of adults (≥ 18 years of age). Acute Bacterial Sinusitiscaused by (Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis). Acute Bacterial Exacerbation of Chronic Bronchitis caused by (Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus, or Moraxella catarrhalis).

Community Acquired Pneumonia caused by (Streptococcus pneumoniae (including multi-drug resistant isolates*), Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus, Klebsiella pneumoniae, Mycoplasma pneumoniae, or Chlamydophila pneumoniae).

Uncomplicated Skin and Skin Structure Infections caused by (methicillin susceptible Staphylococcus aureus or Streptococcus pyogenes). Complicated Skin and Skin Structure Infections caused by (methicillin susceptible Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, or Enterobacter cloacae). Complicated Intra- Abdominal Infections including polymicrobial infections such as abscess caused by (Escherichia coli, Bacteroides fragilis, Streptococcus anginosus, Streptococcus constellatus, Enterococcus faecalis, Proteus mirabilis, Clostridium perfringens, Bacteroides thetaiotaomicron, or Peptostreptococcus species).

Cautions: not recommended for neonates.

Pregnancy: should be avoided in pregnancy because they have been shown to cause arthropathy in animal studies.

Contra-indications: history of hypersensitivity to moxifloxacin or any member of the quinolone class of antimicrobial agents.

Side Effects: Most common taste disturbances, ocular discomfort (including pain, irritation and dryness), hyperaemia. less commonly vomiting, headache, paraesthesia, corneal disorders (including keratitis, erosion, and staining), conjunctival haemorrhage, eyelid erythema, visual disturbances, nasal discomfort, pharyngolaryngeal pain also reported nausea, palpitation, dyspnea, dizziness, raised intra-ocular pressure, photophobia, rash, pruritus. dose 400 mg (orally or as an intravenous infusion) once every 24 hours.