Responsive image

Drug Information

Drug Generic Name LACTULOSE
Drug Class LAXATIVES
Chapter Gastrointestinal System

It contains lactulose 3.35 gm per 5 ml

Indications: Treatment of constipation; prevention and treatment of portal-systemic encephalopathy, including stages of hepatic precoma and coma. It produces increased osmotic pressure within colon and acidifies its contents, resulting in increased stool water content and stool softening. The onset appears after 24 to 48 hr.

Contra-indications: galactosaemia, intestinal obstruction..

Precautions: lactose intolerance, patients on galactose- free diet. diabetes mellitus.

Side effect: Gaseous distention with flatulence or belching, abdominal discomfort and cramping; diarrhea; nausea; vomiting.

Dose: Constipation, initially15 ml twice daily, gradually reduced according to patient's needs. Child, less than 1 year, 2.5 ml. Child 1-5 years, 5 ml. 6-12 years, 10 ml twice daily, gradually reduced.

Hepatic encephalopathy, 30-50 ml 3 times daily, subsequently adjusted to produce 2-3 soft stools daily.

Brand Name
  • Duphalac Syrup Ezilax Syrup
rating - 1 starrating - 2 starrating - 3 starrating - 4 starrating - 5 star