Indications: infections of respiratory tract (except for pneumococcal pneumonia), middle ear (otitis media) and paranasal sinuses (sinusitis), genital organs, abdominal cavity, skin and soft tissues, bones and joints and septicaemia.

Caution elderly patients; renal impairment; epileptics and patients with damage to the central nervous system; ensure adequate fluid intake.

Contra-indications: hypersensitivity to ciprofloxacin or other quinolone chemotherapeutics; pediatrics; nursing or pregnant women.

Side Effects: gastro-intestinal effects like nausea, diarrhoea and vomiting, flatulence; headache, dizziness, sleep disorders; rash, pruritis; rarely dysphagia, pancreatitis, tachycardia, hypotension, oedema, hot flushes, sweating, hyperglycaemia, and erythema nodosum; very rarely movement disorders, tinnitus, vasculitis, and tenosynovitis.

Dose: by mouth, respiratory tract infections, 250-750 mg twice daily, for 7-14 days.

Urinary tract infections, 250-500 mg twice daily. Acute uncomplicated cystitis in women, 100 mg twice daily for 3 days.

A single oral dose of of 500 mg has been suggested for the treatment of gonorrhea.