(Benzhexol Hydrochloride) This is an antimuscarinic drug.

Indications: Parkinsonism, particularly with apathy and depression; drug-induced extrapyramidal effects (but not tardive dyskinesia).

Cautions: cardiovascular, renal and hepatic impairment; psychotic disorders; prostatic hypertrophy; elderly; may cause abuse; avoid abrupt withdrawal.

Contra-indications: gastrointestinal obstruction; tardive dyskinesia.

Side Effects: Constipation, dry mouth, nausea, vomiting, tachycardia, dizziness, confusion, euphoria, hallucinations, impaired memory, anxiety, restlessness, urinary retention, blurred vision and rash.

Dose: 1 mg daily gradually increased; Usual maintenance dose, 5-15 mg daily in 3-4 divided doses.