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Drug Information

Drug Generic Name LEVODOPA WITH CARBIDOPA (Co-careldopa)
Drug Class DRUGS USED IN PARKINSONISM AND RELATED DISORDERS
Chapter Central Nervous System

Indications: parkinsonisim but not drug-induced extrapyramidal effects.

Cautions: pulmonary disease, peptic ulcer, cardiovascular disease, diabetes mellitus, skin melanoma, open-angle glaucoma, asthma, renal and hepatic impairment.

Contra-indications: concomitant MAOI therapy; narrow angle glaucoma.

Side Effects: dyskinesia, muscle twitching and

blepharospasm; mental changes.

Dose: expressed as levodopa, initially, 100 mg 3 times increased by 50-100 mg daily or on alternate days according to response up to 800 mg daily in divided doses

Brand Name
  • Sinemet Tablets (L-Dopa 250 mg & Carbidopa 25 mg)
  • Sinemet-Plus Tablets (L-Dopa 100 mg & Carbidopa 25 mg)
rating - 1 starrating - 2 starrating - 3 starrating - 4 starrating - 5 star