Indications: Parkinsonism (but not drug-induced extrapyramidal symptoms); endocrine diseases. Cautions: Monitor pituitary enlargement, pregnancy, breast feeding, history of psychic or cardiovascular disorders; Raynaud’s syndrome, fibrotic reactions, porphyria, hepatic impairment. Initial hypotensive reactions in some patients.

Contra-indications: hypersensitivity to bromocriptine or other ergot alkaloids, toxaemia of pregnancy: or hypertension in postpartum women or in puerperium.

Side Effects: abnormal involuntary movements; confusional states; nausea, constipation, headache, drowsiness.

Dose: by mouth, First week, 1-1.25 mg at night, Second week, 2-2.25 mg at night, Third week, 2.5 mg twice daily, Fourth week, 2.5 mg 3 times daily, increasing by 2.5 mg every 3-14 days according to response to a usual range of 10-40 mg daily in 3 divided doses, taken with food.