This is a selective serotonin reuptake inhibitor (SSRI).

Indications: depression states; obsessive-compulsive disorder.

Cautions: epilepsy; concurrent electroconvulsive therapy; history of mania; cardiac disease, bleeding disorders; hepatic and renal impairment. that concomitant use of fluvoxamine and theophylline or aminophylline should usually be avoided;

Contra-indications: patients in manic phase.

Side Effects: palpitations, tachycardia, postural.

hypotension; confusion, hallucinations, ataxia, paraesthesia, malaise, taste disturbance, neuroleptic malignant syndrome-like event, abnormal liver function tests, usually symptomatic (discontinue treatment); hypersensitivity reactions.

Dose: depression, initially 50-100 mg daily increased if necessary to max. 300 mg daily.

Obsessive-compulsive disorder, initially 50 mg in the evening increased gradually if necessary after some weeks to max. 300 mg daily (over 150 mg in divided doses); usual maintenance dose 100–300 mg daily; If no improvement in obsessive-compulsive disorder within 10 weeks, treatment should be reconsidered.

CHILD over 8 years initially 25 mg daily increased if necessary in steps of 25 mg every 4–7 days to max. 200 mg daily (over 50 mg in divided doses)