This is a tricyclic antidepressant.

Indications: depressive illness, nocturnal enuresis in children.

Cautions, Contra-indications, Side Effects: see under Amitryptyline HCl.

Dose: initially 75 mg daily in divided doses or as a single dose at bedtime increased gradually to 200 mg (up to 225 mg in hospitalized patients); up to 150 mg may be given as a single dose at bedtime;

Maintenance dose, 75-100 mg daily Elderly patients, 10-25 mg 1-3 times daily. Nocturnal enuresis, child 6-7 years, 25 mg; 8-11 years, 25-50 mg;

Over 11 years, 50-75 mg at bedtime;

Max. period of treatment (including gradual withdrawal) should not exceed 3 months.