Indications: long term management of acute psychosis, mania, or exacerbation of chronic psychosis.

Cautions: porphyria; severe cardiac, respiratory, hepatic or renal disease; in patients with decreased gastrointestinal motility, urinary retention, BPH,

Contra-indications: Acute intoxication with ethanol, barbiturate or opioid, severe CNS depression; coma; sub cortical brain damage, circulatory collapse, blood dyscrasiasa, pheochromocytoma.

Side Effects: drowsiness; anxiety, insomnia, akathisia, extrapyrmidal effects, dizziness, xerostomaia, decreased libido, hypertonia, tremor, weakness.

Dose: by deep IM injection into the gluteal muscle or lateral thigh, 50-150 mg repeated after 2-3 days if necessary. Elderly, 50-100 mg repeated after 2-3 days if necessary. One additional dose may be needed 1 -2 days after the first injection.

Max. cumulative dose, 400 mg per course and max. 4 injections. For necessary maintenance therapy, give oral antipsychotic 2-3 days after last injection or give long antipsychotic depot injection concomitantly with last injection of Zuclopenthixol acetate. Child, not recommended