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Disease Details

Thalassemia
Disease Type Hematology
Description

Thalassemia is an inherited blood disorder caused when the body doesn’t produce enough  hemoglobin,which is an important part of red blood cells

Causes

Thalassemia occurs when there’s an abnormality or mutation in one of the genes involved in hemoglobin production. this genetic abnormality is inhereted from the parents

Symptoms

The symptoms of thalassemia can vary. Some of the most common ones include:

- fatigue and general weakness .
- Shortness of breath .
- Pale skin .
- Yellowing of the skin (jaundice )
- Abnormalities in the facial bones .
- Slow growth .
- abdominal distention
- dark Urine color

Treatments

- Treatment of Thalassemia depends on the type and severity. The treatment of moderate to severe cases include the following
-  frequent blood transfusions,  perhaps every few weeks.
- Stem cell transplantation (bone marrow transplant)

Prevention


In most cases, it cannot be  prevented ; but if you are suffering from Thalassemia, or if you are carrying the genes of thalassemia, it is best to speak to a specialist in genetic diseases .

As well as the obligation to conduct a comprehensive pre marital medical examination to help to reduce the transmission of Thalassemia to offsprinngs  where medical tests show the possibility of indivisuals affected with gene mutation with out showing any symptoms .

Complications

-  patients with major thalassemia disease, may experience complications if not treated properly,  which may include  :
- Delays in the child's development .
- Enlargement of the spleen and abdominal distention  .
-  bones deformities  .
- Exacerbate the problem of anemia .

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