Indications: schizophrenia.

Cautions: cardiovascular and respiratory diseases; pregnancy; infections; renal and hepatic impairment. also excited, agitated, or aggressive patients (even low doses may aggravate symptoms)

Avoid abrupt withdrawal.

Contra-indications: phaeochromocytoma, parkinsonism. also porphyria

Side Effects: Palpitation, hypertension; Dizziness, headache, neuroleptic malignant syndrome, sedation, tardive dyskinesia, galactorrhea, sexual dysfunction, nausea, vomiting, constipation, impotence, cholestatic jaundice, blurred vision,

Dose: 200-400 mg twice daily; max. 800 mg daily in patients with predominantly negative symptoms, and 2.4 g daily in patients with mainly positive symptoms; elderly, initially 100-200 mg daily.